Synthesis and Evaluation of 1,3,5-Triaryl-2-Pyrazoline Derivatives as Potent Dual Inhibitors of Urease and α-Glucosidase Together with Their Cytotoxic, Molecular Modeling and Drug-Likeness Studies

[Image: see text] In the present work, a concise library of 1,3,5-triaryl-2-pyrazolines (2a–2q) was designed and synthesized by employing a multistep strategy, and the newly synthesized compounds were screened for their urease and α-glucosidase inhibitory activities. The compounds (2a–2q) were chara...

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Detalles Bibliográficos
Autores principales: Mehmood, Rabia, Sadiq, Amina, Alsantali, Reem I., Mughal, Ehsan Ullah, Alsharif, Meshari A., Naeem, Nafeesa, Javid, Asif, Al-Rooqi, Munirah M., Chaudhry, Gul-e-Saba, Ahmed, Saleh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811919/
https://www.ncbi.nlm.nih.gov/pubmed/35128286
http://dx.doi.org/10.1021/acsomega.1c06694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811919/
https://www.ncbi.nlm.nih.gov/pubmed/35128286
http://dx.doi.org/10.1021/acsomega.1c06694

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