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Novel humanized monoclonal antibodies for targeting hypoxic human tumors via two distinct extracellular domains of carbonic anhydrase IX

BACKGROUND: Hypoxia in the tumor microenvironment (TME) is often the main factor in the cancer progression. Moreover, low levels of oxygen in tumor tissue may signal that the first- or second-line therapy will not be successful. This knowledge triggers the inevitable search for different kinds of tr...

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Detalles Bibliográficos
Autores principales: Zatovicova, Miriam, Kajanova, Ivana, Barathova, Monika, Takacova, Martina, Labudova, Martina, Csaderova, Lucia, Jelenska, Lenka, Svastova, Eliska, Pastorekova, Silvia, Harris, Adrian L., Pastorek, Jaromir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811981/
https://www.ncbi.nlm.nih.gov/pubmed/35109923
http://dx.doi.org/10.1186/s40170-022-00279-8