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Novel humanized monoclonal antibodies for targeting hypoxic human tumors via two distinct extracellular domains of carbonic anhydrase IX

BACKGROUND: Hypoxia in the tumor microenvironment (TME) is often the main factor in the cancer progression. Moreover, low levels of oxygen in tumor tissue may signal that the first- or second-line therapy will not be successful. This knowledge triggers the inevitable search for different kinds of tr...

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Detalles Bibliográficos
Autores principales:	Zatovicova, Miriam, Kajanova, Ivana, Barathova, Monika, Takacova, Martina, Labudova, Martina, Csaderova, Lucia, Jelenska, Lenka, Svastova, Eliska, Pastorekova, Silvia, Harris, Adrian L., Pastorek, Jaromir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811981/ https://www.ncbi.nlm.nih.gov/pubmed/35109923 http://dx.doi.org/10.1186/s40170-022-00279-8

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