Pre-clinical and clinical studies on the role of RBM3 in muscle-invasive bladder cancer: longitudinal expression, transcriptome-level effects and modulation of chemosensitivity

BACKGROUND: The response to neoadjuvant cisplatin-based chemotherapy (NAC) in muscle-invasive bladder cancer (MIBC) is impaired in up to 50% of patients due to chemoresistance, with no predictive biomarkers in clinical use. The proto-oncogene RNA-binding motif protein 3 (RBM3) has emerged as a putat...

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Detalles Bibliográficos
Autores principales: Wahlin, Sara, Boman, Karolina, Moran, Bruce, Nodin, Björn, Gallagher, William M., Karnevi, Emelie, Jirström, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811987/
https://www.ncbi.nlm.nih.gov/pubmed/35109796
http://dx.doi.org/10.1186/s12885-021-09168-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811987/
https://www.ncbi.nlm.nih.gov/pubmed/35109796
http://dx.doi.org/10.1186/s12885-021-09168-7

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