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Spatial maps of hepatocellular carcinoma transcriptomes highlight an unexplored landscape of heterogeneity and a novel gene signature for survival

BACKGROUND: Hepatocellular carcinoma (HCC) often presents with satellite nodules, rendering current curative treatments ineffective in many patients. The heterogeneity of HCC is a major challenge in personalized medicine. The emergence of spatial transcriptomics (ST) provides a powerful strategy for...

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Detalles Bibliográficos
Autores principales: Zhao, Nan, Zhang, Yanhui, Cheng, Runfen, Zhang, Danfang, Li, Fan, Guo, Yuhong, Qiu, Zhiqiang, Dong, Xueyi, Ban, Xinchao, Sun, Baocun, Zhao, Xiulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812006/
https://www.ncbi.nlm.nih.gov/pubmed/35109839
http://dx.doi.org/10.1186/s12935-021-02430-9