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Comparison of confound adjustment methods in the construction of gene co-expression networks
Adjustment for confounding sources of expression variation is an important preprocessing step in large gene expression studies, but the effect of confound adjustment on co-expression network analysis has not been well-characterized. Here, we demonstrate that the choice of confound adjustment method...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812044/ https://www.ncbi.nlm.nih.gov/pubmed/35115012 http://dx.doi.org/10.1186/s13059-022-02606-0 |