Metformin reduces chondrocyte pyroptosis in an osteoarthritis mouse model by inhibiting NLRP3 inflammasome activation

Osteoarthritis (OA) is an age-related degenerative disease, and its incidence is increasing with the ageing of the population. Metformin, as the first-line medication for the treatment of diabetes, has received increasing attention for its role in OA. The purpose of the present study was to confirm...

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Detalles Bibliográficos
Autores principales: Yan, Jiangbo, Ding, Dong, Feng, Gangning, Yang, Yong, Zhou, Yong, Ma, Long, Guo, Haohui, Lu, Zhidong, Jin, Qunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812147/
https://www.ncbi.nlm.nih.gov/pubmed/35222699
http://dx.doi.org/10.3892/etm.2022.11146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812147/
https://www.ncbi.nlm.nih.gov/pubmed/35222699
http://dx.doi.org/10.3892/etm.2022.11146

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