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Mesenchymal stem cells combined with autocrosslinked hyaluronic acid improve mouse ovarian function by activating the PI3K-AKT pathway in a paracrine manner

BACKGROUND: Declining ovarian function in advance-aged women and in premature ovarian insufficiency (POI) patients seriously affects quality of life, and there is currently no effective treatment to rescue ovarian function in clinic. Stem cell transplantation is a promising therapeutic strategy for...

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Detalles Bibliográficos
Autores principales: Jiao, Wenlin, Mi, Xin, Yang, Yajuan, Liu, Ran, Liu, Qiang, Yan, Tao, Chen, Zi-Jiang, Qin, Yingying, Zhao, Shidou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812195/
https://www.ncbi.nlm.nih.gov/pubmed/35109928
http://dx.doi.org/10.1186/s13287-022-02724-3