Cargando…
Mesenchymal stem cells combined with autocrosslinked hyaluronic acid improve mouse ovarian function by activating the PI3K-AKT pathway in a paracrine manner
BACKGROUND: Declining ovarian function in advance-aged women and in premature ovarian insufficiency (POI) patients seriously affects quality of life, and there is currently no effective treatment to rescue ovarian function in clinic. Stem cell transplantation is a promising therapeutic strategy for...
Autores principales: | Jiao, Wenlin, Mi, Xin, Yang, Yajuan, Liu, Ran, Liu, Qiang, Yan, Tao, Chen, Zi-Jiang, Qin, Yingying, Zhao, Shidou |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812195/ https://www.ncbi.nlm.nih.gov/pubmed/35109928 http://dx.doi.org/10.1186/s13287-022-02724-3 |
Ejemplares similares
-
HGF Secreted by Mesenchymal Stromal Cells Promotes Primordial Follicle Activation by Increasing the Activity of the PI3K-AKT Signaling Pathway
por: Mi, Xin, et al.
Publicado: (2022) -
In situ repair abilities of human umbilical cord–derived mesenchymal stem cells and autocrosslinked hyaluronic acid gel complex in rhesus monkeys with intrauterine adhesion
por: Wang, Lingjuan, et al.
Publicado: (2020) -
CPEB1 deletion is not a common explanation for premature ovarian insufficiency in a Chinese cohort
por: Jiao, Wenlin, et al.
Publicado: (2020) -
Transcription–replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability
por: Yang, Yajuan, et al.
Publicado: (2022) -
TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis
por: Huang, Chengzi, et al.
Publicado: (2023)