Mutational signatures reveal ternary relationships between homologous recombination repair, APOBEC, and mismatch repair in gynecological cancers

BACKGROUND: Revealing the impacts of endogenous and exogenous mutagenesis processes is essential for understanding the etiology of somatic genomic alterations and designing precise prognostication and treatment strategies for cancer. DNA repair deficiency is one of the main sources of endogenous mut...

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Detalles Bibliográficos
Autores principales: Farmanbar, Amir, Firouzi, Sanaz, Kneller, Robert, Khiabanian, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812249/
https://www.ncbi.nlm.nih.gov/pubmed/35109853
http://dx.doi.org/10.1186/s12967-022-03259-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812249/
https://www.ncbi.nlm.nih.gov/pubmed/35109853
http://dx.doi.org/10.1186/s12967-022-03259-0

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