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The Thioesterase ACOT1 as a Regulator of Lipid Metabolism in Type 2 Diabetes Detected in a Multi-Omics Study of Human Liver

Type 2 diabetes (T2D) is characterized by pathophysiological alterations in lipid metabolism. One strategy to understand the molecular mechanisms behind these abnormalities is to identify cis-regulatory elements (CREs) located in chromatin-accessible regions of the genome that regulate key genes. In...

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Detalles Bibliográficos
Autores principales: Cavalli, Marco, Diamanti, Klev, Dang, Yonglong, Xing, Pengwei, Pan, Gang, Chen, Xingqi, Wadelius, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812507/
https://www.ncbi.nlm.nih.gov/pubmed/34520261
http://dx.doi.org/10.1089/omi.2021.0093