Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer

High-grade serous ovarian carcinoma (HGSOC) is a cancer with dismal prognosis due to the limited effectiveness of existing chemo- and immunotherapies. To elucidate mechanisms mediating sensitivity or resistance to these therapies, we developed a fast and flexible autochthonous mouse model based on s...

Descripción completa

Detalles Bibliográficos
Autores principales: Paffenholz, Stella V., Salvagno, Camilla, Ho, Yu-Jui, Limjoco, Matthew, Baslan, Timour, Tian, Sha, Kulick, Amanda, de Stanchina, Elisa, Wilkinson, John E., Barriga, Francisco M., Zamarin, Dmitriy, Cubillos-Ruiz, Juan R., Leibold, Josef, Lowe, Scott W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812522/
https://www.ncbi.nlm.nih.gov/pubmed/35082152
http://dx.doi.org/10.1073/pnas.2117754119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812522/
https://www.ncbi.nlm.nih.gov/pubmed/35082152
http://dx.doi.org/10.1073/pnas.2117754119

Ejemplares similares