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The endoplasmic reticulum chaperone BiP is a closure-accelerating cochaperone of Grp94

Hsp70 and Hsp90 chaperones provide protein quality control to the cytoplasm, endoplasmic reticulum (ER), and mitochondria. Hsp90 activity is often enhanced by cochaperones that drive conformational changes needed for ATP-dependent closure and capture of client proteins. Hsp90 activity is also enhanc...

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Detalles Bibliográficos
Autores principales: Huang, Bin, Sun, Ming, Hoxie, Reyal, Kotler, Judy L. M., Friedman, Larry J., Gelles, Jeff, Street, Timothy O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812556/
https://www.ncbi.nlm.nih.gov/pubmed/35078937
http://dx.doi.org/10.1073/pnas.2118793119