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The endoplasmic reticulum chaperone BiP is a closure-accelerating cochaperone of Grp94
Hsp70 and Hsp90 chaperones provide protein quality control to the cytoplasm, endoplasmic reticulum (ER), and mitochondria. Hsp90 activity is often enhanced by cochaperones that drive conformational changes needed for ATP-dependent closure and capture of client proteins. Hsp90 activity is also enhanc...
Autores principales: | Huang, Bin, Sun, Ming, Hoxie, Reyal, Kotler, Judy L. M., Friedman, Larry J., Gelles, Jeff, Street, Timothy O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812556/ https://www.ncbi.nlm.nih.gov/pubmed/35078937 http://dx.doi.org/10.1073/pnas.2118793119 |
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