In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain

The intracellular misfolding and accumulation of alpha-synuclein into structures collectively called Lewy pathology (LP) is a central phenomenon for the pathogenesis of synucleinopathies, including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Understanding the molecular architecture...

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Detalles Bibliográficos
Autores principales: Killinger, Bryan A., Marshall, Lee L., Chatterjee, Diptaman, Chu, Yaping, Bras, Jose, Guerreiro, Rita, Kordower, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812572/
https://www.ncbi.nlm.nih.gov/pubmed/35082147
http://dx.doi.org/10.1073/pnas.2114405119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812572/
https://www.ncbi.nlm.nih.gov/pubmed/35082147
http://dx.doi.org/10.1073/pnas.2114405119

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