Cargando…
In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain
The intracellular misfolding and accumulation of alpha-synuclein into structures collectively called Lewy pathology (LP) is a central phenomenon for the pathogenesis of synucleinopathies, including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Understanding the molecular architecture...
Autores principales: | Killinger, Bryan A., Marshall, Lee L., Chatterjee, Diptaman, Chu, Yaping, Bras, Jose, Guerreiro, Rita, Kordower, Jeffrey H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812572/ https://www.ncbi.nlm.nih.gov/pubmed/35082147 http://dx.doi.org/10.1073/pnas.2114405119 |
Ejemplares similares
-
Correction for Killinger et al., In situ proximity labeling identifies Lewy pathology molecular interactions in the human brain
Publicado: (2022) -
Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson’s disease model
por: Chatterjee, Diptaman, et al.
Publicado: (2018) -
Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let’s talk about the lipids in the room
por: Killinger, Bryan A., et al.
Publicado: (2019) -
Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis
por: Killinger, Bryan A., et al.
Publicado: (2023) -
The Genetics of Dementia with Lewy Bodies: Current Understanding and Future Directions
por: Orme, Tatiana, et al.
Publicado: (2018)