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CD81 costimulation skews CAR transduction toward naive T cells

Adoptive cellular therapy using chimeric antigen receptors (CARs) has revolutionized our treatment of relapsed B cell malignancies and is currently being integrated into standard therapy. The impact of selecting specific T cell subsets for CAR transduction remains under investigation. Previous studi...

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Detalles Bibliográficos
Autores principales: Schultz, Liora M., Czerwinski, Debra K., Levy, Ronald, Levy, Shoshana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812682/
https://www.ncbi.nlm.nih.gov/pubmed/35091467
http://dx.doi.org/10.1073/pnas.1910844119