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Trojan horse treatment based on PEG-coated extracellular vesicles to deliver doxorubicin to melanoma in vitro and in vivo

Tailoring extracellular vesicles (EVs) as targeted drug delivery systems to enhance the therapeutic efficacy showed superior advantage over liposomal therapies. Herein, we developed a novel nanotool for targeting B16.F10 murine melanoma, based on EVs stabilized with Polyethylene glycol (PEG) and loa...

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Detalles Bibliográficos
Autores principales: Patras, Laura, Ionescu, Aura Elena, Munteanu, Cristian, Hajdu, Renata, Kosa, Andreea, Porfire, Alina, Licarete, Emilia, Rauca, Valentin Florian, Sesarman, Alina, Luput, Lavinia, Bulzu, Paul, Chiroi, Paul, Tranca, Rares Andrei, Meszaros, Marta-Szilvia, Negrea, Giorgiana, Barbu-Tudoran, Lucian, Potara, Monica, Szedlacsek, Stefan, Banciu, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812761/
https://www.ncbi.nlm.nih.gov/pubmed/34964693
http://dx.doi.org/10.1080/15384047.2021.2003656