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Trojan horse treatment based on PEG-coated extracellular vesicles to deliver doxorubicin to melanoma in vitro and in vivo
Tailoring extracellular vesicles (EVs) as targeted drug delivery systems to enhance the therapeutic efficacy showed superior advantage over liposomal therapies. Herein, we developed a novel nanotool for targeting B16.F10 murine melanoma, based on EVs stabilized with Polyethylene glycol (PEG) and loa...
Autores principales: | Patras, Laura, Ionescu, Aura Elena, Munteanu, Cristian, Hajdu, Renata, Kosa, Andreea, Porfire, Alina, Licarete, Emilia, Rauca, Valentin Florian, Sesarman, Alina, Luput, Lavinia, Bulzu, Paul, Chiroi, Paul, Tranca, Rares Andrei, Meszaros, Marta-Szilvia, Negrea, Giorgiana, Barbu-Tudoran, Lucian, Potara, Monica, Szedlacsek, Stefan, Banciu, Manuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812761/ https://www.ncbi.nlm.nih.gov/pubmed/34964693 http://dx.doi.org/10.1080/15384047.2021.2003656 |
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