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Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis

Liver fibrosis is a common pathologic stage of the development of liver failure. It has showed that exosomes loaded with therapeutic circRNAs can be manufactured in bulk by exosome secreted cells in vitro, thus enabling personalized treatment. This study aimed to investigate the role of exosome-base...

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Detalles Bibliográficos
Autores principales: Ma, Li, Wei, Junfeng, Zeng, Yanli, Liu, Junping, Xiao, Erhui, Kang, Yuehua, Kang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812765/
https://www.ncbi.nlm.nih.gov/pubmed/35099348
http://dx.doi.org/10.1080/10717544.2022.2030428