Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics

Therapeutic monoclonal antibodies and their derivatives are key components of clinical pipelines in the global biopharmaceutical industry. The availability of large datasets of antibody sequences, structures, and biophysical properties is increasingly enabling the development of predictive models an...

Descripción completa

Detalles Bibliográficos
Autores principales: Khetan, Rahul, Curtis, Robin, Deane, Charlotte M., Hadsund, Johannes Thorling, Kar, Uddipan, Krawczyk, Konrad, Kuroda, Daisuke, Robinson, Sarah A., Sormanni, Pietro, Tsumoto, Kouhei, Warwicker, Jim, Martin, Andrew C.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812776/
https://www.ncbi.nlm.nih.gov/pubmed/35104168
http://dx.doi.org/10.1080/19420862.2021.2020082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812776/
https://www.ncbi.nlm.nih.gov/pubmed/35104168
http://dx.doi.org/10.1080/19420862.2021.2020082

Ejemplares similares