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Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics
Therapeutic monoclonal antibodies and their derivatives are key components of clinical pipelines in the global biopharmaceutical industry. The availability of large datasets of antibody sequences, structures, and biophysical properties is increasingly enabling the development of predictive models an...
Autores principales: | Khetan, Rahul, Curtis, Robin, Deane, Charlotte M., Hadsund, Johannes Thorling, Kar, Uddipan, Krawczyk, Konrad, Kuroda, Daisuke, Robinson, Sarah A., Sormanni, Pietro, Tsumoto, Kouhei, Warwicker, Jim, Martin, Andrew C.R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812776/ https://www.ncbi.nlm.nih.gov/pubmed/35104168 http://dx.doi.org/10.1080/19420862.2021.2020082 |
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