Cargando…

Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion

PARP1 and Chk1 inhibitors have been shown to be synergistic in different cancer models in relatively short time treatment modes. However, the consequences of long-term/repeated treatments with the combinations in cancer models remain unclear. In this study, the synergistic cytotoxicity of their comb...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Ne, Li, Meng-Zhu, Wang, Li-Min, Chen, Hua-Dong, Song, Shan-Shan, Miao, Ze-Hong, He, Jin-Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812781/
https://www.ncbi.nlm.nih.gov/pubmed/35000525
http://dx.doi.org/10.1080/15384047.2021.2024414