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Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion
PARP1 and Chk1 inhibitors have been shown to be synergistic in different cancer models in relatively short time treatment modes. However, the consequences of long-term/repeated treatments with the combinations in cancer models remain unclear. In this study, the synergistic cytotoxicity of their comb...
Autores principales: | Guo, Ne, Li, Meng-Zhu, Wang, Li-Min, Chen, Hua-Dong, Song, Shan-Shan, Miao, Ze-Hong, He, Jin-Xue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812781/ https://www.ncbi.nlm.nih.gov/pubmed/35000525 http://dx.doi.org/10.1080/15384047.2021.2024414 |
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