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Absence of association between host genetic mutations in the ORAI1 gene and COVID-19 fatality

The calcium ion channel ORAI1 has emerged as a promising therapeutic target for the Coronavirus Disease 19 (COVID-19)-associated pneumonia, and a pharmacological inhibitor of ORAI1 has now reached clinical trials for severe COVID-19 pneumonia. Whether ORAI1 itself is associated with an increased ris...

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Detalles Bibliográficos
Autores principales: Shawer, Heba, Cheng, Chew W., Bailey, Marc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812896/
https://www.ncbi.nlm.nih.gov/pubmed/35113933
http://dx.doi.org/10.1371/journal.pone.0263303