Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis

BACKGROUND: Epidemiological studies have reported conflicting findings on the potential adverse effects of long-term antihypertensive medication use on cancer risk. Naturally occurring variation in genes encoding antihypertensive drug targets can be used as proxies for these targets to examine the e...

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Detalles Bibliográficos
Autores principales: Yarmolinsky, James, Díez-Obrero, Virginia, Richardson, Tom G., Pigeyre, Marie, Sjaarda, Jennifer, Paré, Guillaume, Walker, Venexia M., Vincent, Emma E., Tan, Vanessa Y., Obón-Santacana, Mireia, Albanes, Demetrius, Hampe, Jochen, Gsur, Andrea, Hampel, Heather, Pai, Rish K., Jenkins, Mark, Gallinger, Steven, Casey, Graham, Zheng, Wei, Amos, Christopher I., Smith, George Davey, Martin, Richard M., Moreno, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812899/
https://www.ncbi.nlm.nih.gov/pubmed/35113855
http://dx.doi.org/10.1371/journal.pmed.1003897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812899/
https://www.ncbi.nlm.nih.gov/pubmed/35113855
http://dx.doi.org/10.1371/journal.pmed.1003897

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