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AT-752, a double prodrug of a guanosine nucleotide analog, inhibits yellow fever virus in a hamster model

Yellow fever virus (YFV) is a zoonotic pathogen re-emerging in parts of the world, causing a viral hemorrhagic fever associated with high mortality rates. While an effective vaccine is available, having an effective antiviral against YFV is critical against unexpected outbreaks, or when vaccination...

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Detalles Bibliográficos
Autores principales: Lin, Kai, Good, Steven S., Julander, Justin G., Weight, Abbie E., Moussa, Adel, Sommadossi, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812913/
https://www.ncbi.nlm.nih.gov/pubmed/35073319
http://dx.doi.org/10.1371/journal.pntd.0009937