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In vivo interferon-gamma induced changes in gene expression dramatically alter neutrophil phenotype

The cytokine Interferon-γ (IFN-γ) exerts powerful immunoregulatory effects on the adaptive immune system and also enhances functions of the neutrophil (PMN). The clinical use of IFN-γ has been driven by the finding that its administration to patients with chronic granulomatous disease (CGD) results...

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Detalles Bibliográficos
Autores principales: Ambruso, Daniel R., Briones, Natalie J., Baroffio, Angelina F., Murphy, John R., Tran, Alexander D., Gowan, Katherine, Sanford, Bridget, Ellison, Michael, Jones, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812922/
https://www.ncbi.nlm.nih.gov/pubmed/35113934
http://dx.doi.org/10.1371/journal.pone.0263370