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In vivo interferon-gamma induced changes in gene expression dramatically alter neutrophil phenotype
The cytokine Interferon-γ (IFN-γ) exerts powerful immunoregulatory effects on the adaptive immune system and also enhances functions of the neutrophil (PMN). The clinical use of IFN-γ has been driven by the finding that its administration to patients with chronic granulomatous disease (CGD) results...
Autores principales: | Ambruso, Daniel R., Briones, Natalie J., Baroffio, Angelina F., Murphy, John R., Tran, Alexander D., Gowan, Katherine, Sanford, Bridget, Ellison, Michael, Jones, Kenneth L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812922/ https://www.ncbi.nlm.nih.gov/pubmed/35113934 http://dx.doi.org/10.1371/journal.pone.0263370 |
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