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Lateral access mechanism of LPA receptor probed by molecular dynamics simulation

G-protein-coupled receptors (GPCR) are a family of membrane receptors that play important roles in the regulation of various physiological phenomena. LPA receptors (LPA(1-6)) are members of the class A GPCRs, which transduce a lysophosphatidic acid (LPA) signal across the cell membrane and evoke var...

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Detalles Bibliográficos
Autores principales: Suenaga, Rieko, Takemoto, Mizuki, Inoue, Asuka, Ishitani, Ryuichiro, Nureki, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812926/
https://www.ncbi.nlm.nih.gov/pubmed/35113924
http://dx.doi.org/10.1371/journal.pone.0263296