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Lateral access mechanism of LPA receptor probed by molecular dynamics simulation
G-protein-coupled receptors (GPCR) are a family of membrane receptors that play important roles in the regulation of various physiological phenomena. LPA receptors (LPA(1-6)) are members of the class A GPCRs, which transduce a lysophosphatidic acid (LPA) signal across the cell membrane and evoke var...
Autores principales: | Suenaga, Rieko, Takemoto, Mizuki, Inoue, Asuka, Ishitani, Ryuichiro, Nureki, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812926/ https://www.ncbi.nlm.nih.gov/pubmed/35113924 http://dx.doi.org/10.1371/journal.pone.0263296 |
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