Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 immune responses

Nucleoside modified mRNA combined with Acuitas Therapeutics’ lipid nanoparticles (LNPs) has been shown to support robust humoral immune responses in many preclinical animal vaccine studies and later in humans with the SARS-CoV-2 vaccination. We recently showed that this platform is highly inflammato...

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Detalles Bibliográficos
Autores principales: Ndeupen, Sonia, Bouteau, Aurélie, Herbst, Christopher, Qin, Zhen, Jacobsen, Sonya, Powers, Nicholas E., Hutchins, Zachary, Kurup, Drishya, Diba, Leila Zabihi, Watson, Megan, Ramage, Holly, Igyártó, Botond Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812972/
https://www.ncbi.nlm.nih.gov/pubmed/35073387
http://dx.doi.org/10.1371/journal.ppat.1010255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812972/
https://www.ncbi.nlm.nih.gov/pubmed/35073387
http://dx.doi.org/10.1371/journal.ppat.1010255

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