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Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 immune responses
Nucleoside modified mRNA combined with Acuitas Therapeutics’ lipid nanoparticles (LNPs) has been shown to support robust humoral immune responses in many preclinical animal vaccine studies and later in humans with the SARS-CoV-2 vaccination. We recently showed that this platform is highly inflammato...
Autores principales: | Ndeupen, Sonia, Bouteau, Aurélie, Herbst, Christopher, Qin, Zhen, Jacobsen, Sonya, Powers, Nicholas E., Hutchins, Zachary, Kurup, Drishya, Diba, Leila Zabihi, Watson, Megan, Ramage, Holly, Igyártó, Botond Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812972/ https://www.ncbi.nlm.nih.gov/pubmed/35073387 http://dx.doi.org/10.1371/journal.ppat.1010255 |
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