Altered type 1 interferon responses in alloimmunized and nonalloimmunized patients with sickle cell disease

Patients with sickle cell disease (SCD) have a high prevalence of RBC alloimmunization. However, underlying mechanisms are poorly understood. Given that proinflammatory type 1 interferons (IFNα/β) and interferon stimulated genes (ISGs) promote alloimmunization in mice, we hypothesized that IFNα/β ma...

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Detalles Bibliográficos
Autores principales: Madany, Emaan, Lee, June, Halprin, Chelsea, Seo, Jina, Baca, Nicole, Majlessipour, Fataneh, Hendrickson, Jeanne E., Pepkowitz, Samuel H., Hayes, Chelsea, Klapper, Ellen, Gibb, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Sickle Cell, Thrombosis, and Benign Haematology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813163/
https://www.ncbi.nlm.nih.gov/pubmed/35128535
http://dx.doi.org/10.1002/jha2.270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813163/
https://www.ncbi.nlm.nih.gov/pubmed/35128535
http://dx.doi.org/10.1002/jha2.270

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