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Altered type 1 interferon responses in alloimmunized and nonalloimmunized patients with sickle cell disease

Patients with sickle cell disease (SCD) have a high prevalence of RBC alloimmunization. However, underlying mechanisms are poorly understood. Given that proinflammatory type 1 interferons (IFNα/β) and interferon stimulated genes (ISGs) promote alloimmunization in mice, we hypothesized that IFNα/β ma...

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Detalles Bibliográficos
Autores principales:	Madany, Emaan, Lee, June, Halprin, Chelsea, Seo, Jina, Baca, Nicole, Majlessipour, Fataneh, Hendrickson, Jeanne E., Pepkowitz, Samuel H., Hayes, Chelsea, Klapper, Ellen, Gibb, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Sickle Cell, Thrombosis, and Benign Haematology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813163/ https://www.ncbi.nlm.nih.gov/pubmed/35128535 http://dx.doi.org/10.1002/jha2.270

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