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Key Determinants of Cell-Mediated Immune Responses: A Randomized Trial of High Dose Vs. Standard Dose Split-Virus Influenza Vaccine in Older Adults

Background: Efforts to improve influenza vaccine effectiveness in older adults have resulted in some successes, such as the introduction of high-dose split-virus influenza vaccine (HD-SVV), yet studies of cell-mediated immune responses to these vaccines remain limited. We have shown that granzyme B...

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Detalles Bibliográficos
Autores principales: Verschoor, Chris P., Haynes, Laura, Pawelec, Graham, Loeb, Mark, Andrew, Melissa K., Kuchel, George A., McElhaney, Janet E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813165/
https://www.ncbi.nlm.nih.gov/pubmed/35128529
http://dx.doi.org/10.3389/fragi.2021.649110