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Key Determinants of Cell-Mediated Immune Responses: A Randomized Trial of High Dose Vs. Standard Dose Split-Virus Influenza Vaccine in Older Adults
Background: Efforts to improve influenza vaccine effectiveness in older adults have resulted in some successes, such as the introduction of high-dose split-virus influenza vaccine (HD-SVV), yet studies of cell-mediated immune responses to these vaccines remain limited. We have shown that granzyme B...
Autores principales: | Verschoor, Chris P., Haynes, Laura, Pawelec, Graham, Loeb, Mark, Andrew, Melissa K., Kuchel, George A., McElhaney, Janet E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813165/ https://www.ncbi.nlm.nih.gov/pubmed/35128529 http://dx.doi.org/10.3389/fragi.2021.649110 |
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