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PGF2α-FP Receptor Ameliorates Senescence of VSMCs in Vascular Remodeling by Src/PAI-1 Signal Pathway

Senescence in vascular smooth muscle cells (VSMCs) is involved in vascular remodeling of aged mice. ProstaglandinF2α- (PGF2α-) FP receptor plays a critical role in cardiovascular diseases (CVDs), hypertension, and cardiac fibrosis. However, its role in senescence-induced arteriosclerosis is yet to b...

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Detalles Bibliográficos
Autores principales: Hu, Bo-ang, Sai, Wen-wen, Yuan, Jun, Lan, Hong-tao, Qi, Jia, Wang, Di, Zhang, Wei, Wang, Zhi-hao, Zhong, Ming, Shang, Yuan-yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813271/
https://www.ncbi.nlm.nih.gov/pubmed/35126810
http://dx.doi.org/10.1155/2022/2908261