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Hdac8 Inhibitor Alleviates Transverse Aortic Constriction-Induced Heart Failure in Mice by Downregulating Ace1

BACKGROUND: Heart failure is characterized by activation of the renin-angiotensin-aldosterone system, which is involved in the regulation of cardiac hypertrophy and hypertension. Recently, we reported that Hdac8 inhibition alleviates isoproterenol-induced and angiotensin II-induced cardiac hypertrop...

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Detalles Bibliográficos
Autores principales: Zhao, Tingwei, Kee, Hae Jin, Kee, Seung-Jung, Jeong, Myung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813277/
https://www.ncbi.nlm.nih.gov/pubmed/35126818
http://dx.doi.org/10.1155/2022/6227330