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The Improvement of Sepsis-Associated Encephalopathy by P2X7R Inhibitor through Inhibiting the Omi/HtrA2 Apoptotic Signaling Pathway

The pathogenesis of sepsis-associated encephalopathy (SAE) involves many aspects, including intracellular peroxidative stress damage, mitochondrial dysfunction, and cell apoptosis. In this study, we mainly explored the influence of P2X7R on the cognitive function of SAE and its molecular mechanism....

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Detalles Bibliográficos
Autores principales: Wang, Kaifang, Sun, Meiyan, Juan, Zhaodong, Zhang, Jianxin, Sun, Yingui, Wang, Guizhi, Wang, Chunling, Li, Yanjing, Kong, Wenwen, Fan, Lulu, Zhang, Yue, Zhao, Hongxiang, Zhao, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813303/
https://www.ncbi.nlm.nih.gov/pubmed/35126784
http://dx.doi.org/10.1155/2022/3777351