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The Improvement of Sepsis-Associated Encephalopathy by P2X7R Inhibitor through Inhibiting the Omi/HtrA2 Apoptotic Signaling Pathway
The pathogenesis of sepsis-associated encephalopathy (SAE) involves many aspects, including intracellular peroxidative stress damage, mitochondrial dysfunction, and cell apoptosis. In this study, we mainly explored the influence of P2X7R on the cognitive function of SAE and its molecular mechanism....
Autores principales: | Wang, Kaifang, Sun, Meiyan, Juan, Zhaodong, Zhang, Jianxin, Sun, Yingui, Wang, Guizhi, Wang, Chunling, Li, Yanjing, Kong, Wenwen, Fan, Lulu, Zhang, Yue, Zhao, Hongxiang, Zhao, Xiaoyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813303/ https://www.ncbi.nlm.nih.gov/pubmed/35126784 http://dx.doi.org/10.1155/2022/3777351 |
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