Pharmacokinetics and Exposure–Response of Vosoritide in Children with Achondroplasia

BACKGROUND AND OBJECTIVE: Vosoritide, an analog of C-type natriuretic peptide, has been developed for the treatment of children with achondroplasia. The pharmacokinetics of vosoritide and relationships between plasma exposure and efficacy, biomarkers, and safety endpoints were evaluated in a phase I...

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Detalles Bibliográficos
Autores principales: Chan, Ming Liang, Qi, Yulan, Larimore, Kevin, Cherukuri, Anu, Seid, Lori, Jayaram, Kala, Jeha, George, Fisheleva, Elena, Day, Jonathan, Huntsman-Labed, Alice, Savarirayan, Ravi, Irving, Melita, Bacino, Carlos A., Hoover-Fong, Julie, Ozono, Keiichi, Mohnike, Klaus, Wilcox, William R., Horton, William A., Henshaw, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813707/
https://www.ncbi.nlm.nih.gov/pubmed/34431071
http://dx.doi.org/10.1007/s40262-021-01059-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813707/
https://www.ncbi.nlm.nih.gov/pubmed/34431071
http://dx.doi.org/10.1007/s40262-021-01059-1

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