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Exogenous melatonin prevents type 1 diabetes mellitus–induced bone loss, probably by inhibiting senescence

SUMMARY: Exogenous melatonin inhibited the senescence of preosteoblast cells in type 1 diabetic (T1D) mice and those cultured in high glucose (HG) by multiple regulations. Exogenous melatonin had a protective effect on diabetic osteoporosis, which may depend on the inhibition of senescence. INTRODUC...

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Detalles Bibliográficos
Autores principales: Gong, Z., Da, W., Tian, Y., Zhao, R., Qiu, S., Wu, Q., Wen, K., Shen, L., Zhou, R., Tao, L., Zhu, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813725/
https://www.ncbi.nlm.nih.gov/pubmed/34519833
http://dx.doi.org/10.1007/s00198-021-06061-8