A CTCF-Binding Element and Histone Deacetylation Cooperatively Maintain Chromatin Loops, Linking to Long-Range Gene Regulation in Cancer Genomes

BACKGROUND: Genes spanning long chromosomal domains are coordinately regulated in human genome, which contribute to global gene dysregulation and carcinogenesis in cancer. It has been noticed that epigenetic modification and chromatin architecture may participate in the regulation process. However,...

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Detalles Bibliográficos
Autores principales: Tang, Ran, Li, Yiqun, Han, Fang, Li, Zhenzhi, Lin, Xiaoyu, Sun, Haoxiu, Zhang, Xiaoqing, Jiang, Qinghua, Nie, Huan, Li, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813737/
https://www.ncbi.nlm.nih.gov/pubmed/35127534
http://dx.doi.org/10.3389/fonc.2021.821495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813737/
https://www.ncbi.nlm.nih.gov/pubmed/35127534
http://dx.doi.org/10.3389/fonc.2021.821495

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