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Reliability of a novel approach for reference-based cell type estimation in human placental DNA methylation studies
The placenta is a central organ during early development, influencing trajectories of health and disease. DNA methylation (DNAm) studies of human placenta improve our understanding of how its function relates to disease risk. However, DNAm studies can be biased by cell type heterogeneity, so it is e...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813756/ https://www.ncbi.nlm.nih.gov/pubmed/35113241 http://dx.doi.org/10.1007/s00018-021-04091-3 |