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Reliability of a novel approach for reference-based cell type estimation in human placental DNA methylation studies

The placenta is a central organ during early development, influencing trajectories of health and disease. DNA methylation (DNAm) studies of human placenta improve our understanding of how its function relates to disease risk. However, DNAm studies can be biased by cell type heterogeneity, so it is e...

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Detalles Bibliográficos
Autores principales:	Dieckmann, Linda, Cruceanu, Cristiana, Lahti-Pulkkinen, Marius, Lahti, Jari, Kvist, Tuomas, Laivuori, Hannele, Sammallahti, Sara, Villa, Pia M., Suomalainen-König, Sanna, Rancourt, Rebecca C., Plagemann, Andreas, Henrich, Wolfgang, Eriksson, Johan G., Kajantie, Eero, Entringer, Sonja, Braun, Thorsten, Räikkönen, Katri, Binder, Elisabeth B., Czamara, Darina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813756/ https://www.ncbi.nlm.nih.gov/pubmed/35113241 http://dx.doi.org/10.1007/s00018-021-04091-3

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