Cladribine as a Potential Object of Nucleoside Transporter-Based Drug Interactions

Cladribine is a nucleoside analog that is phosphorylated in its target cells (B and T-lymphocytes) to its active triphosphate form (2-chlorodeoxyadenosine triphosphate). Cladribine tablets 10 mg (Mavenclad(®)), administered for up to 10 days per year in 2 consecutive years (3.5-mg/kg cumulative dose...

Descripción completa

Detalles Bibliográficos
Autores principales: Hermann, Robert, Krajcsi, Peter, Fluck, Markus, Seithel-Keuth, Annick, Bytyqi, Afrim, Galazka, Andrew, Munafo, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813788/
https://www.ncbi.nlm.nih.gov/pubmed/34894346
http://dx.doi.org/10.1007/s40262-021-01089-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813788/
https://www.ncbi.nlm.nih.gov/pubmed/34894346
http://dx.doi.org/10.1007/s40262-021-01089-9

Ejemplares similares