The HGR motif is the antiangiogenic determinant of vasoinhibin: implications for a therapeutic orally active oligopeptide

The hormone prolactin acquires antiangiogenic and antivasopermeability properties after undergoing proteolytic cleavage to vasoinhibin, an endogenous prolactin fragment of 123 or more amino acids that inhibits the action of multiple proangiogenic factors. Preclinical and clinical evidence supports t...

Descripción completa

Detalles Bibliográficos
Autores principales: Robles, Juan Pablo, Zamora, Magdalena, Siqueiros-Marquez, Lourdes, Adan-Castro, Elva, Ramirez-Hernandez, Gabriela, Nuñez, Francisco Freinet, Lopez-Casillas, Fernando, Millar, Robert P., Bertsch, Thomas, Martínez de la Escalera, Gonzalo, Triebel, Jakob, Clapp, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813873/
https://www.ncbi.nlm.nih.gov/pubmed/34097181
http://dx.doi.org/10.1007/s10456-021-09800-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813873/
https://www.ncbi.nlm.nih.gov/pubmed/34097181
http://dx.doi.org/10.1007/s10456-021-09800-x

Ejemplares similares