cFLIP downregulation is an early event required for endoplasmic reticulum stress-induced apoptosis in tumor cells

Protein misfolding or unfolding and the resulting endoplasmic reticulum (ER) stress frequently occur in highly proliferative tumors. How tumor cells escape cell death by apoptosis after chronic ER stress remains poorly understood. We have investigated in both two-dimensional (2D) cultures and multic...

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Detalles Bibliográficos
Autores principales: Mora-Molina, Rocío, Stöhr, Daniela, Rehm, Markus, López-Rivas, Abelardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813907/
https://www.ncbi.nlm.nih.gov/pubmed/35115486
http://dx.doi.org/10.1038/s41419-022-04574-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813907/
https://www.ncbi.nlm.nih.gov/pubmed/35115486
http://dx.doi.org/10.1038/s41419-022-04574-6

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