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The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom’s syndrome helicase for efficient disruption of D-loops

Homologous recombination (HR) is a ubiquitous and efficient process that serves the repair of severe forms of DNA damage and the generation of genetic diversity during meiosis. HR can proceed via multiple pathways with different outcomes that may aid or impair genome stability and faithful inheritan...

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Detalles Bibliográficos
Autores principales: Harami, Gábor M., Pálinkás, János, Seol, Yeonee, Kovács, Zoltán J., Gyimesi, Máté, Harami-Papp, Hajnalka, Neuman, Keir C., Kovács, Mihály
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813930/
https://www.ncbi.nlm.nih.gov/pubmed/35115525
http://dx.doi.org/10.1038/s41467-022-28208-9